Conducting weird scientific experiments crazed Dr James Brewster (Bela Lugosi) aided by his colleague Dr Randall has managed to transform himself into a hairy stooped over ape man. Desperately seeking a cure Brewster believes only an injection of a recently drawn human spinal fluid will prove effective. With Randall refusing to help him it falls to Brewster and his captive gorilla to find appropriate donors - living or dead!
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Crazed scientist Dr Brewster (Bela Lugosi) slaves away in his basement, hidden from the outside world, determined to produce a serum based on a gorilla's spinal fluid. When Brewster tries the serum out on himself, he first develops a thick growth of facial hair, then discovers that his spine is contorting into the posture of an ape...